Lab77 Peptides: MOTS-c (Lyophilized Powder)
Mitochondrial-Derived Peptide (MDP) for Metabolic Homeostasis & Cellular Energy Research
Lab77 Peptides MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is an analytical-grade, 16-amino acid mitochondrial-derived peptide engineered specifically for in-vitro metabolic regulation studies, AMP-activated protein kinase (AMPK) activation assays, and nuclear-mitochondrial communication research. Synthesized via Solid-Phase Peptide Synthesis (SPPS), MOTS-c regulates metabolic homeostasis at the cellular level by targeting the folate cycle and purine biosynthesis pathways.
When sourcing a MOTS-c research peptide UK laboratories can depend on for repeatable, publication-grade results, sequence purity and structural stability are paramount. Every batch of Lab77 MOTS-c stock undergoes independent third-party audits to confirm precise molecular weight, sequence identity, and quantitative vial content.
Technical Specifications & Chemical Profile | Lab77 Peptides MOTS-c
| Technical Parameter | Specification Standard |
| Chemical Name | MOTS-c (Mitochondrial-Derived Peptide) |
| Sequence Backbone | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-NH2 |
| Molecular Formula | $\text{C}_{101}\text{H}_{152}\text{N}_{28}\text{O}_{22}\text{S}_2$ |
| Molecular Weight | $\sim 2174.6 \text{ g/mol}$ |
| Purity Grade | $\ge 98\%$ (HPLC Verified) |
| Physical Appearance | Lyophilized White Powder (Vacuum Sealed) |
| Storage Standard | Desiccated at $-20^\circ\text{C}$ (Shield from moisture and ambient light) |
Key Scientific Research Applications | Lab77 Peptides MOTS-c
MOTS-c is a primary focal point in bioenergetics and age-related metabolic research due to its unique ability to translocate to the cell nucleus under metabolic stress and regulate nuclear gene expression.
Researchers utilizing MOTS-c research peptide UK compounds focus on primary analytical vectors, including:
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AMPK Pathway Activation: Measuring downstream phosphorylation of AMP-activated protein kinase to evaluate cellular energy sensing and glucose utilization.
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Folate-Purine Biosynthesis Modulation: Investigating AICAR accumulation and metabolic flux through the 1C (one-carbon) folate cycle.
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Nuclear-Mitochondrial Crosstalk: Mapping MOTS-c nuclear translocation kinetics during metabolic stress and ROS exposure in cell models.
Analytical Verification: Janoshik Tested & Certified
To safeguard your laboratory assays against sequence truncation artifacts or solvent residues, every batch of our MOTS-c research peptide UK inventory is audited independently by Janoshik Analytical.
[ Solid-Phase Synthesis ] ──► [ Independent Janoshik Audit ] ──► [ Verified COA Released ]
Verified Batch Metrics:
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High-Performance Liquid Chromatography (HPLC): Guarantees sequence purity ($\ge 98\%$), ruling out unreacted peptide fragments.
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Mass Spectrometry (MS): Validates exact molecular mass ($\sim 2174.6 \text{ Da}$) and sequence alignment.
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Quantity Auditing: Verifies precise milligram mass per vial to eliminate micro-dosing variances during assay preparation.
Verify Your Batch: Every vial includes a unique batch code. Access our [Janoshik COA Verification Portal] to view original HPLC chromatograms and mass spectra prior to laboratory reconstitution.
Reconstitution & Handling Guidance | Lab77 Peptides MOTS-c
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Reconstitution Media: Reconstitute using sterile, laboratory-grade Bacteriostatic Water or sterile 0.9% sodium chloride buffer.
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Solubility Protocol: Allow the vial to reach room temperature before solvent introduction. Gently swirl the vial to dissolve the lyophilized cake—avoid violent agitation or vortexing to preserve peptide tertiary structures.
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Storage Protocol: Store unopened lyophilized vials desiccated at $-20^\circ\text{C}$. After reconstitution, maintain liquid stock solutions at $2^\circ\text{C}$ to $8^\circ\text{C}$ and utilize within your laboratory’s designated testing timeframe.
Why Source MOTS-c from Lab77 Peptides UK?
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Direct UK Inventory: Domestic dispatch eliminates border holds, customs delays, and transit-related thermal degradation.
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Full Batch Traceability: Every lot is directly linked to an unaltered, public Certificate of Analysis (COA).
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Strict Research-Grade Mandate: Purpose-built exclusively for life science research, academic institutions, and analytical laboratories.
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[Add MOTS-c Vial to Cart] (Internal Link to Product Checkout)
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[View Research Injector Pens & Accessories] (Internal Link to Hardware Category)
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[Access Janoshik COA Lookup Portal] (Internal Link to Verification Portal)
Compliance Disclaimer
This product is supplied strictly for in-vitro research, laboratory experimentation, and scientific analytical use. It is not a drug, biological product, or medical agent, nor is it intended or approved for human consumption, clinical trials, or therapeutic administration.
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