Lab77 Peptides: Methylcobalamin (Active Vitamin B12)
Active Coenzyme Corrinoid for One-Carbon Metabolism, Epigenetics & Neurobiology Research
Lab77 Peptides Methylcobalamin is an analytical-grade, highly bioactive form of Vitamin B12 (cobalamin) engineered specifically for in-vitro cellular methylation assays, neuroprotective pathways, and metabolic cofactor research. Unlike synthetic cyanocobalamin, b12 methylcobalamin possesses a methyl ligand, allowing it to act directly as a co-substrate for methionine synthase without requiring intracellular enzymatic cleavage.
When sourcing research reagents—whether benchmarking cellular uptake dynamics against traditional clinical protocols like a methycobal injection, evaluating systemic coenzyme bioavailability compared to b12 iv therapy models, or studying target cell response to an injection of methylcobalamin in laboratory assays—chemical purity and light protection are critical. Every batch of Lab77 Methylcobalamin undergoes independent third-party audits to confirm precise quantitative content, molecular identity, and structural integrity.
Technical Specifications & Chemical Profile | Lab77 Peptides Methylcobalamin
| Technical Parameter | Specification Standard |
| Chemical Name | $\text{Methylcobalamin / MeCbl (Co-methylcobalamin)}$ |
| CAS Registry Number | 13422-55-4 |
| Molecular Formula | $\text{C}_{63}\text{H}_{91}\text{CoN}_{13}\text{O}_{14}\text{P}$ |
| Molecular Weight | $\sim 1344.40 \text{ g/mol}$ |
| Purity Grade | $\ge 98\%$ (HPLC Verified) |
| Physical Appearance | Dark Red Lyophilized Powder / Crystalline Solid |
| Storage Standard | Desiccated at $-20^\circ\text{C}$ (Strictly shield from ambient light and UV exposure) |
Key Scientific Research Applications | Lab77 Peptides Methylcobalamin
Methylcobalamin is a vital cofactor in transmethylation cycles and neurobiological pathways, making it an essential analytical tool across several life science disciplines.
Researchers utilizing b12 methylcobalamin focus on key analytical vectors, including:
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Methionine Synthase Kinetics: Measuring conversion of homocysteine to methionine to evaluate cellular methylation capacity and SAM (S-adenosylmethionine) regeneration.
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Neuronal Regeneration & Myelinogenesis: Investigating axonal transport, Schwann cell proliferation, and neuroprotective signaling in nerve culture models.
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DNA Synthesis & Epigenetics: Modeling single-carbon transfer mechanisms required for purine/pyrimidine biosynthesis and genomic DNA methylation.
Analytical Verification: Janoshik Tested & Certified
To safeguard your laboratory assays against photo-degradation products (such as hydroxocobalamin conversion), solvent impurities, or quantitative variances, every batch of our research inventory is audited independently by Janoshik Analytical.
[ Solid-Phase Synthesis ] ──► [ Independent Janoshik Audit ] ──► [ Verified COA Released ]
Verified Batch Metrics:
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High-Performance Liquid Chromatography (HPLC): Guarantees active coenzyme purity ($\ge 98\%$), confirming minimal degradation or analogue presence.
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Mass Spectrometry (MS): Validates exact molecular mass ($\sim 1344.40 \text{ Da}$) and corrin ring organometallic structure.
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Quantity Auditing: Verifies precise milligram mass per vial to eliminate micro-dosing variances during assay preparation.
Verify Your Batch: Every vial includes a unique lot number. Access our [Janoshik COA Verification Portal] to view original HPLC chromatograms and mass spectra prior to laboratory reconstitution.
Reconstitution & Handling Guidance
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Reconstitution Media: Reconstitute using sterile, laboratory-grade Bacteriostatic Water or sterile 0.9% sodium chloride buffer.
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Photolytic Protection: Methylcobalamin is light-sensitive. Prepare and handle reconstituted solutions under subdued lighting conditions or use light-blocking laboratory vials.
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Storage Protocol: Store unopened lyophilized vials desiccated at $-20^\circ\text{C}$ in dark conditions. Following reconstitution, store liquid stock solutions at $2^\circ\text{C}$ to $8^\circ\text{C}$ (protected from light) and utilize within your laboratory’s designated testing timeframe.
Why Source Methylcobalamin from Lab77 Peptides UK?
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Direct UK Inventory: Domestic dispatch eliminates border holds, customs delays, and light/thermal degradation during extended transit.
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Full Batch Traceability: Every lot is directly linked to an unaltered, public Certificate of Analysis (COA).
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Strict Research-Grade Mandate: Formulated exclusively for life science research, academic institutions, and analytical laboratories.
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[Add Methylcobalamin B12 Vial to Cart] (Internal Link to Product Checkout)
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[View Research Injector Pens & Accessories] (Internal Link to Hardware Category)
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[Access Janoshik COA Lookup Portal] (Internal Link to Verification Portal)
Compliance Disclaimer
This product is supplied strictly for in-vitro research, laboratory experimentation, and scientific analytical use. It is not a drug, biological product, or medical agent, nor is it intended or approved for human consumption, clinical trials, or therapeutic administration.




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