Lab77 Peptides Thymosin Alpha-1 vial

£30.00

Category: Lab77 Peptides vial

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Lab77 Peptides: Thymosin Alpha-1 (Lyophilized Powder)

28-Amino Acid Immunomodulatory Peptide for T-Cell Maturation, Innate Immune Signaling & Viral Defense Research

Lab77 Peptides Thymosin Alpha-1 (

\text{T}\alpha1

/ Zadaxin analogue) is an analytical-grade, highly purified 28-amino acid peptide naturally derived from prothymosin alpha. Engineered specifically for in-vitro immunomodulatory assays, dendritic cell activation studies, and cell-mediated immune dynamics, thymosin alpha 1 peptide plays a central regulatory role in modulating cell-mediated immunity, promoting T-cell progenitor differentiation, and balancing pro- and anti-inflammatory cytokine signaling.

When establishing experimental protocols to measure cytotoxic T-lymphocyte (

CD8^+

) proliferation, natural killer (

NK

) cell cytotoxicity, or toll-like receptor (

TLR

) pathway activation, chemical stability and exact sequence purity are vital. Every batch of Lab77 Thymosin Alpha-1 undergoes rigorous independent third-party audits to guarantee absolute structural integrity, sequence fidelity, and zero baseline contaminants.

Technical Specifications & Chemical Profile | Lab77 Peptides Thymosin Alpha-1

Technical Parameter	Specification Standard
Chemical Name	Thymosin Alpha-1 ( $\text{T}\alpha1$ / Thymalfasin)
CAS Registry Number	62304-98-7
Sequence Backbone	`Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH`
Molecular Formula	$\text{C}_{129}\text{H}_{215}\text{N}_{33}\text{O}_{55}$
Molecular Weight	$\sim 3108.3 \text{ g/mol}$
Purity Grade	$\ge 98\%$ (HPLC Verified)
Physical Appearance	Lyophilized White Powder (Vacuum Sealed)
Storage Standard	Desiccated at $-20^\circ\text{C}$ (Shield from heat, light, and moisture)

Key Scientific Research Applications | Lab77 Peptides Thymosin Alpha-1

Thymosin Alpha-1 is a cornerstone reagent across immunology, oncology, and infectious disease models due to its ability to restore immune homeostatic balance without triggering hyper-inflammatory cytokine storms.

Researchers utilizing Lab77 thymosin alpha 1 peptide focus on primary analytical vectors, including:

T-Cell Differentiation & Maturation: Quantifying double-negative thymocyte transition into mature $CD4^+$ helper and $CD8^+$ cytotoxic T-cell populations in thymic stromal cultures.
Toll-Like Receptor Activation: Evaluating $TLR-7$ and $TLR-9$ signaling pathways in dendritic cells, leading to increased interferon-alpha ( $\text{IFN-}\alpha$ ) and interleukin-2 ( $\text{IL-2}$ ) production.
Oncological Immune Responses: Assessing MHC Class I molecule upregulation on tumor cell surfaces to enhance cytotoxic recognition.
Intracellular Antioxidant Defense: Measuring glutathione peroxidase and superoxide dismutase upregulation during oxidative stress assays.

Analytical Verification: Janoshik Tested & Certified

To safeguard your laboratory assays against truncated sequences, incorrect terminal acetylation, or mass discrepancies, every batch of our inventory is independently audited by Janoshik Analytical.

   [ Solid-Phase Peptide Synthesis ] ──► [ Independent Janoshik Audit ] ──► [ Verified COA Released ]

Verified Batch Metrics:

High-Performance Liquid Chromatography (HPLC): Guarantees peptide sequence purity ( $\ge 98\%$ ), confirming the absence of deamidation or truncated impurities.
Mass Spectrometry (MS): Validates exact molecular mass ( $\sim 3108.3 \text{ Da}$ ) and N-terminal acetylation.
Quantity Auditing: Verifies precise milligram mass per vial to eliminate micro-dosing variances when preparing stock solutions for cell culture assays.

Verify Your Batch: Every vial features a unique lot code. Access our [Janoshik COA Verification Portal] to view original HPLC chromatograms and mass spectra prior to laboratory reconstitution.

Reconstitution & Handling Guidance | Lab77 Peptides Thymosin Alpha-1

Reconstitution Media: Reconstitute using sterile, laboratory-grade Bacteriostatic Water or sterile 0.9% sodium chloride buffer.
Solubility Protocol: Allow the vial to reach room temperature before solvent introduction. Gently swirl the vial until completely dissolved—avoid aggressive vortexing to preserve secondary peptide conformation.
Storage Protocol: Store unopened lyophilized vials desiccated at $-20^\circ\text{C}$ . Following reconstitution, store liquid stock solutions at $2^\circ\text{C}$ to $8^\circ\text{C}$ and utilize within your laboratory’s designated testing timeframe.

Why Source Thymosin Alpha-1 from Lab77 Peptides UK?

Direct UK Inventory: Domestic dispatch eliminates border holds, import tariffs, and thermal degradation during long transit windows.
Full Batch Traceability: Every lot is directly linked to an unaltered, public Certificate of Analysis (COA).
Strict Research-Grade Mandate: Formulated exclusively for life science research, academic institutions, and analytical laboratories.
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Compliance Disclaimer

This product is supplied strictly for in-vitro research, laboratory experimentation, and scientific analytical use. It is not a drug, biological product, or medical agent, nor is it intended or approved for human consumption, clinical trials, or therapeutic administration.