Lab77 Peptides Ara-290 vial

£35.00

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Lab77 Peptides: Ara-290 / Cibinetide (Lyophilized Powder)

Selective Innate Repair Receptor (IRR) Agonist for Neuroprotection, Inflammation & Small Fiber Neuropathy Research

Lab77 Peptides Ara-290 (Cibinetide / pyroglutamate helix B surface peptide) is an analytical-grade, 11-amino acid non-erythropoietic peptide derived from the helix B domain of erythropoietin (EPO). Engineered specifically for in-vitro neuroprotection assays, macrophage modulation studies, and tissue repair research, Ara-290 selectively binds to the Innate Repair Receptor (IRR)—a heteromer of EPO receptor and

\text{CD131}

(

\beta

-common receptor) subunits—without stimulating erythropoiesis or increasing hematocrit.

When sourcing an ara-290 peptide UK laboratories rely on for publication-grade, reproducible data, sequence purity and structural integrity are essential. Every batch of Lab77 ara-290 UK stock undergoes independent third-party audits to confirm precise molecular weight, sequence identity, and quantitative vial content.

Technical Specifications & Chemical Profile | Lab77 Peptides Ara-290

Technical Parameter	Specification Standard
Chemical Name	Ara-290 / Cibinetide (Pyroglutamate Helix B Surface Peptide)
CAS Registry Number	1208243-50-8
Sequence Backbone	`Pyroglutamate-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser`
Molecular Formula	$\text{C}_{51}\text{H}_{84}\text{N}_{16}\text{O}_{21}$
Molecular Weight	$\sim 1257.32 \text{ g/mol}$
Purity Grade	$\ge 98\%$ (HPLC Verified)
Physical Appearance	Lyophilized White Powder (Vacuum Sealed)
Storage Standard	Desiccated at $-20^\circ\text{C}$ (Shield from moisture and heat)

Key Scientific Research Applications | Lab77 Peptides Ara-290

Ara-290 is a vital research tool in neurobiology and immunological signaling due to its ability to selectively activate anti-inflammatory and anti-apoptotic pathways downstream of tissue injury.

Researchers seeking to buy ara-290 UK analytical compounds focus on key primary vectors, including:

Innate Repair Receptor (IRR) Signaling: Mapping CD131 heterodimerization and downstream Akt/GSK-3$\beta$ survival pathway activation in damaged cell lines.
Pro-Inflammatory Cytokine Suppression: Evaluating NF- $\kappa\text{B}$ inhibition and reduction of TNF- $\alpha$ , IL-6, and IL-1$\beta$ release in activated microglia and macrophages.
Small Fiber Neuronal Repair: Assessing neurite outgrowth kinetics, Schwann cell response, and axonal protection in distal neuropathy models.

Analytical Verification: Janoshik Tested & Certified

To safeguard your laboratory assays against sequence truncation artifacts, unreacted reagents, or mass discrepancies, every batch of our cibinetide research peptide UK stock is independently audited by Janoshik Analytical.

   [ Solid-Phase Synthesis ] ──► [ Independent Janoshik Audit ] ──► [ Verified COA Released ]

Verified Batch Metrics:

High-Performance Liquid Chromatography (HPLC): Guarantees sequence purity ( $\ge 98\%$ ), confirming the absence of unreacted peptide fragments.
Mass Spectrometry (MS): Validates exact molecular mass ( $\sim 1257.32 \text{ Da}$ ) and structural sequence alignment.
Quantity Auditing: Verifies precise milligram mass per vial to eliminate micro-dosing variances during assay preparation.

Verify Your Batch: Every vial includes a unique batch code. Access our [Janoshik COA Verification Portal] to view original HPLC chromatograms and mass spectra prior to laboratory reconstitution.

Reconstitution & Handling Guidance | Lab77 Peptides Ara-290

Reconstitution Media: Reconstitute using sterile, laboratory-grade Bacteriostatic Water or sterile 0.9% sodium chloride buffer.
Solubility Protocol: Allow the vial to equalize to room temperature before solvent introduction. Gently swirl the vial to dissolve the lyophilized cake—avoid violent agitation or vortexing to preserve tertiary structural alignment.
Storage Protocol: Store unopened lyophilized vials desiccated at $-20^\circ\text{C}$ . Following reconstitution, store liquid stock solutions at $2^\circ\text{C}$ to $8^\circ\text{C}$ and utilize within your laboratory’s designated testing timeframe.

Why Source Ara-290 from Lab77 Peptides UK?

Direct UK Inventory: Domestic dispatch eliminates border holds, customs delays, and thermal degradation during long transit windows.
Full Batch Traceability: Every lot is directly linked to an unaltered, public Certificate of Analysis (COA).
Strict Research-Grade Mandate: Formulated exclusively for life science research, academic institutions, and analytical laboratories.
[Add Ara-290 Vial to Cart] (Internal Link to Product Checkout)
[View Research Injector Pens & Accessories] (Internal Link to Hardware Category)
[Access Janoshik COA Lookup Portal] (Internal Link to Verification Portal)

Compliance Disclaimer

This product is supplied strictly for in-vitro research, laboratory experimentation, and scientific analytical use. It is not a drug, biological product, or medical agent, nor is it intended or approved for human consumption, clinical trials, or therapeutic administration.